2017. - V. 31. - N 11(192). - P. 129-131
M.A. Khavpachev, V.V. Kireev, T.A. Akopova,
In this paper, simultaneous action of pressure and shear deformation onto polymers to obtain the unsaturated derivatives of chitosan is proposed. The method eliminates the use of solvents and does not require melt of reactive mixtures and, thus, is a convenient and effective way of targeted chemical modification of infusible and low soluble polysaccharides. The conducted investigations have shown that mechanical activation of the solid reagents at the chosen conditions of solid-state synthesis allows to cut significantly their consumption, duration and temperature of the process and leads to formation of unsaturated derivatives of chitosan with higher yield of the products as compared with similar process in the organic solvent medium.
First page of the article:
chitosan mechanical activation pressure and shear deformation solid-state synthesis tissue engineering unsaturated derivatives of chitosan давление и сдвиговые деформации механическая активация непредельные производные хитозана твёрдофазный синтез тканевая инженерия хитозан