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- Articles 3759
- Volumes 11
- Issues 120
UDK: 544.35+539.21
2016. - V. 30. - N 12(181). - P. 43-45
Tatyana Yu. Nagovitsina, Marina Yu. Koroleva, Evgeny V. Yurtov,
THE STABILITY OF NANOEMULSIONS WITH ENCAPSULATED DRUGS IN CASE OF THEIR STABILIZATION BY TWEEN 60 AND SPAN 60
Nanocapsules based on nanoemulsions stabilized by Tween 60 and Span 60 were described in this paper. The formation of a solid-like adsorption layer on the surface of oil droplets took place in nanoemulsion. As a result emulsion stability towards Ostwald repining and coalescence increased significantly. The encapsulation of drugs: (+)-α-tocopherol, hydrocortisone, nimesulide, curcumin had little effect on the stability of nanoemulsions. The average diameter of oil droplets remained almost unchanged after 70 days.
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Keywords
(+)-α-tocopherol (+)-α-токоферол curcumin hydrocortisone nanocapsules nanoemulsions nanoencapsulation nimesulide Span 60 Tween 60 гидрокортизон куркумин нанокапсулирование нанокапсулы Наноэмульсии нимесулид
