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UDK: 544.35+539.21

2016. - V. 30. - N 12(181). - P. 43-45

Tatyana Yu. Nagovitsina, Marina Yu. Koroleva, Evgeny V. Yurtov,

THE STABILITY OF NANOEMULSIONS WITH ENCAPSULATED DRUGS IN CASE OF THEIR STABILIZATION BY TWEEN 60 AND SPAN 60

Nanocapsules based on nanoemulsions stabilized by Tween 60 and Span 60 were described in this paper. The formation of a solid-like adsorption layer on the surface of oil droplets took place in nanoemulsion. As a result emulsion stability towards Ostwald repining and coalescence increased significantly. The encapsulation of drugs: (+)-α-tocopherol, hydrocortisone, nimesulide, curcumin had little effect on the stability of nanoemulsions. The average diameter of oil droplets remained almost unchanged after 70 days.

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First page of the article:

УСТОЙЧИВОСТЬ НАНОЭМУЛЬСИЙ, СТАБИЛИЗИРОВАННЫХ TWEEN 60 И SPAN 60, С ИНКАПСУЛИРОВАННЫМИ ЛЕКАРСТВЕННЫМИ ВЕЩЕСТВАМИ

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Keywords

(+)-α-tocopherol   (+)-α-токоферол   curcumin   hydrocortisone   nanocapsules   nanoemulsions   nanoencapsulation   nimesulide   Span 60   Tween 60   гидрокортизон   куркумин   нанокапсулирование   нанокапсулы   Наноэмульсии   нимесулид  


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