2016. - V. 30. - N 1(170). - P. 44-45
Nikolay Vyacheslavovich Osipenko, Sergey Anatolyevich Maklakov,
In order to obtain an analog of anti-inflammatory drug indomethacin perfected chain of syntheses. Examing the methods for 4-nitroacetanilide by nitration of acetanilide and acetylation of 4-nitroaniline. Reduction of 4-nitroacetanilide is received 4-aminoacetanilide. With diazotization and subsequent reduction it synthesized hexachlorostannate 4-acetaminophenylhidrazine. His interaction with the ethyl levulinic acid obtained 5-acetamino-5-methylindole-3-acetic acid.
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